Photo Christine Chappard

Position: Senior Researcher
Administrative attachment: INSERM

Leader of "Clinical research for osteo-articular diseases" research axis

Expertise

Trabecular bone, cortical bone, cartilage, bone micro-architecture, osteoporosis, osteoarthrosis, biomedical imaging, biomarkers, X-rays, computed tomography, synchrotron imaging

Curriculum Vitae

Education

1995 - Specialized Degree in Rheumatology University Paris Descartes
1996 - Doctor in Medicine University Paris Descartes
1995 - Master degree in biomedical engineering from the Technological University of Compiègne
2000 - PhD Thesis in Biological and Medical Engineering Sciences from the University of Paris XII,
2006 - Accreditation to conduct Research in life sciences University of Orléans

Medical career

1990-1994: Medical Resident in Paris Hospitals
1996-2000: Hospital-University Assistant in Physiology Hôpital Broussais Hotel Dieu
2000-2002: Medical Doctor in the Nuclear Medicine department, Hôpital Européen Georges Pompidou, Paris

Research positions

2000-2002: Post-doctoral position in the unit U356 Inserm Physiology and renal cellular endocrinology, Paris Descartes University, Paris
2004-present: Recruited as Inserm researcher
2004-2009: U658 Inserm Characterization of Bone Tissue by Imaging (CTI), Orléans University
2009-Present: UMR 7052 CNRS Osteoarticular Biology, Bioengineering and Bioimaging (B3OA), Paris Diderot University

Other activities

2014- Director of the federative research structure FRE 3616 CNRS - Paris Diderot University Imaging for osteo-articular research (IMOSAR)
2014 - In charge of radiation protection for B3OA and IMOSAR
2014-2017 Member of scientific council of Medical University Paris Diderot
2017- Member of section 28 CNRS (Pharmacology, bio-engineering, imaging, biotechnology)

Selected publications

Chappard C, Peyrin F, Bonassie A, Lemineur G, Brunet-Imbault B, Lespessailles E, Benhamou CL. Subchondral Bone Micro-Architectural Alterations In Osteoarthritis : a Synchrotron Micro-Computed Tomography Study. Osteoarthritis and Cartilage 2006, 14: 215-223. Link for the publication .

Rocher E, Chappard C, Jaffre C, Benhamou CL, Courteix D. Bone mineral density in prepubertal obese and control children: relation to body weight, lean mass, and fat mass. J Bone Miner Metab 2008, 26: 73-8. Link for the publication .

Chappard C, Bousson V, Bergot C, Mitton D, Moser T, Marchadier A, Benhamou L, Laredo JD. Cross-Sectional Study of Texture Analysis and Geometric Measurements on Plain Radiographs versus Bone Mineral Density for Predicting Femoral Fracture Load. Radiology 2010, 255:536-43. Link for the publication .

Chappard C, Bensalah S, Oliver C, Gouttenoire JP, Marchadier A, Benhamou CL, Peyrin F. 3D characterization of pores in cortical of elderly human femur in different locations by synchrotron micro-computed tomography images. Osteoporos Int. 2013 Mar;24(3):1023-33. Link for the publication .

Ostertag A, Peyrin F, Fernandez S, Laredo JD, de Vernejoul MC, Chappard C. Cortical Measurements of the Tibia from High Resolution Peripheral Quantitative Computed Tomography Images: A Comparison with Synchrotron Radiation Micro-Computed Tomography. Bone 2014, 63: 7-14. Link for the publication .

PubMed link for C. Chappard's publications

Contact

+33 (0)1 57 27 85 34